Weightloss | Saxenda Ozempic Rybelsus | Online UK

Weight Loss

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What is medicated weight loss?

This is a new programme, which you may have seen in the news since last year (2022). But why choose a medication to aid weight loss and is it safe for aesthetic purposes? How many times have you heard "just eat less, move more"? It's not always that easy for a lot of people. In fact, the majority of diets (over 65%) fail because people still feel hungry - you're forcing yourself to starve your body of what it is craving and what it wants.

These weight loss medications are a synthetic hormone regulating the body's natural hunger hormone, GLP-1. The release of GLP-1 acts on the receptors in the appetite-control section of the brain, reducing your appetite. It slows down gastric emptying, keeping you fuller for longer which further reduces your appetite.

It also helps your pancreas release just the correct amount of insulin to deal with your body's glucogon, meaning it works differently for each person's individual needs. This allows sugars and carbs to be broken down in an effective way without causing a "sugar crash", which therefore avoids those quick-fix sugary cravings and a hunger for carbs. It also helps reduce leptin levels, which is a key hormone in causing a metabolism slow-down.

When you diet, your appetite does not shrink to match the dietary requirements. Portion control has a major impact on the ability of a person to effectively lose weight. With a suppressed appetite, you will naturally start eating smaller portions. Your stomach will start to shrink, effectively reducing the amount of food required to fill your stomach and the amount of food needed to appease your appetite.

Once you're comfortable with the dietary side of things, you can begin to incorporate exercise into the programme. We offer a range of quick, simple home-based workout programmes and an exercise crib sheet to help you burn off hose calories.

The programme is not just a quick-fix. It comprises of a holistic approach including nutrition & exercise. This is so that once you finish the programme, you can keep the weight off naturally with healthy eating & light to moderate exercise.

Please see the below table for a comparison:

How does it work?

The medications mimic a natural hormone already found in your body (GLP-1). They work in three key ways to reduce your appetite.

It blocks a key hunger hormone telling your brain that you are hungry, whilst also helping to reduce leptin resistance (a hormone which can help off-set weight gain by increasing satiety aka fullness, and speed up your metabolism to help regulate the levels of fatty tissue in your body). This also helps stop the weight from coming straight back on when you stop the jab.
It slows down the gastric emptying process, meaning that your body takes longer to process food and it is fuller for longer. This means your body does not need as much intake as normal as it works off the food it has.
The medication helps to speed up your metabolism and increase fat burning by reducing glucogon & reducing insulin resistance. This promotes normal blood glucose levels, the liver metabolism of glucose and helps adipose tissue burn fat in a safe and controlled method without causing a sugar-crash. This avoids the urges for quick-fix sugary foods.

This all helps to reduce the risk of the so-called "starvation mode" and other side effects like ketoacidosis, as you will be burning off a mixture of stored carbs & fats.

Unlike fad diets which tend to starve the body when it's shouting out for food, the medication reduces your body's desire to get more food, which makes it easier to make healthier choices and to reduce calories. It also stops leptin levels from lowering due to "starvation". Low leptin levels can cause increased hunger & a slower metabolism!

The medications are Saxenda, Ozempic, Wegovy, Rybelsus, Trulicity and Mounjaro.

How much can I lose?

The average weight loss per person is always different. Clinical trials for the medications have shown a range of weight loss between 8lbs and 19lbs.

In the latest Semaglutide study, 75% of participants lost 10% of their body weight. During clinical trials for Liraglutide, 80% of those who used Saxenda kept the weight for over a year.

The key is not to compare yourself to others losing weight - focus on yourself, your goals and your progress. Every person is different.

How do I get it?

This is a prescription-only medication and it must be prescribed to ensure your safety & suitability. There are three simple steps:

Screening: you complete our easy-to-use online health form.
Payment: if you are happy with all the information provided and you wish to go ahead, payment is made.
Dispatch - the medication is prescribed, dispensed and dispatched to you.

For payment, you can either proceed to our checkout after the health form and complete your order. Or you can wait for your health form to be assessed and we will send you a manual invoice via email. Our payment provider is PayPal, so your transaction is safe and protected by PayPal Buyer Guarantee. You can also choose to Pay In 3 payments rather than all at once. You do not need a PayPal account to pay - you can checkout as a Guest and pay with your normal credit or debit card.

Once payment has been processed and your health form has been approved, we will send the medication to you on one of your selected delivery days. We cannot guarantee next working day due to the current stock shortage of these medications.

We use UK prescribers to prescribe the medication and get your medication dispensed from UK registered & regulated pharmacies. At the moment, we operate only online through our website. There are no brick & mortar pharmacy premises or physical clinics.

Who can use it?

The medication can be used for those with BMI over 25. We take into account a range of factors such as:

BMI
Medical History
Current Medication
Body measurements
Eating habits
Past diets
Current exercise levels

The programme is not suitable for:

Under 18's

Ladies who are breastfeeding, pregnant or actively trying to get pregnant.

Type 1 diabetics

Anyone with a history of pancreatitis or thyroid tumours

Anyone with direct family members who have had thyroid cancer

How do you send the medication?

If you have been prescribed a medication for weight loss, we will send this via next day Special Delivery with Tracking. You will be sent the tracking details the day before delivery once your item is confirmed with the courier for collection.

Certain couriers will email you the day of delivery with a time frame of when to expect your package (e.g. APC, DPD and UPS) whilst Royal Mail always aim to deliver before 1pm. If there are any issues with your delivery, please contact us immediately via email so everything is in writing for us to liaise with the relevant courier.

How do you send the items that need to be kept chilled?

We send all injectable medications in temperature-controlled packaging with ice packs. Internal audit data from the packaging companies we use state that the products are kept cool for up to 48 hours. Your item usually arrives within 24 hours of packaging.

What happens if the cold chain breaks?

If the cold chain breaks during transit (e.g. there is a delay in delivery or you miss the delivery) or you forget to unpack the medication to put in the fridge before first usage, please do not become alarmed. Should your item break the cold chain, it will start the same chemical process as when you use the pen for the first time (e.g. piercing the medicated vial with your first needle for your first injection).

What this means is that you must use your medication within the recommended time frame (not the expiry date shown on your medication) and you no longer have to store the pen in the fridge (after first use or if your medication breaks the cold chain) - however, it will do no harm to continue to store the pen in the fridge. Some people prefer the medication to be cool upon injection, whereas others prefer it to be at ambient (room) temperature.

If you believe your medication has broken the cold chain prior to first use, please email us immediately so that we can advise you appropriately and, if necessary, inform you of the recommended time frame to use your medication.

Are there side effects?

Like any medication, there are the risks of side effects. The most common side effects are transient - this means that they only last for a couple of days whilst your body adjusts to the medication. 40-60% of clients experience no side effects, whilst others experience one or two mild side effects e.g. a dry mouth or a mild headache. Our aftercare literature (booklet & online aftercare) offers advice on how to deal with the most common side side effects. You also receive a Patient Information Leaflet detailing the ins & outs of the medication, including all side effects. Our team is also available for you to contact should you need any advice or support.

Please see the individual medication pages for the relevant side effects.

Will I get support whilst using the medication?

Absolutely! Being overweight is a very common problem. More than 2/3 adults in the UK are either overweight or obese. Excess weight is linked to several serious health problems such as heart disease, diabetes and stroke.

We sent every new starter a Starter Pack, which has everything you need to get going. We’ll get in touch regularly to see how you're getting on and we are always available if you need any advice or support, or if you need any help with making the lifestyle changes you need to manage your weight over the long-term.

After you start any treatment with us, we’ll check in with you to see how you’re getting on. If it’s going well, we can look at arranging repeat courses for you.

Do I need to see my doctor before using these medications?

Whilst you do not need to see your doctor or inform them that you are taking this medication, we advise that it would be sensible to keep your GP informed of any medications you use privately so that they have the full picture of your medical history.

Is this right for me?

That is ultimately a decision for you to make once you have received all the relevant information and have been screened for suitability to use these medications. We recommend everyone to try all conventional methods first before turning to medication for aesthetic weight loss. The NHS offer a Free 12 Week programme, whilst other companies offer diet & exercise focused programmes. If you have weighed up all the information and feel this is the correct route for you, and you are deemed safe & suitable to commence onto treatment, you are able to make an informed decision and consent to starting treatment.

You can also check your current BMI using our free BMI calculator here: What is MyBMI

Receiving & Storing the medication:

All items (except Saxenda) should arrive in the original manufacturer's packaging - completely sealed and unopened. Saxenda may arrive in a pharmacy's own box/packaging if they have to 'break up' a box of 5 pens to accommodate 5 individual patients. Each item must contain the manufacturer's Patient Information Leaflet, and clearly display the product code, batch number and expiry date.

If you have ordered an injection, please ensure you store the product in the fridge before first use. After first use, you can store it at room temperature up to 30 degrees or keep it in the fridge - please ensure you use Saxenda within 30 days and Ozempic/Wegovy/Trulicity within 6 weeks. If your item breaks the cold chain (e.g. is left out of the fridge for too long), please do not be alarmed - this will start the same countdown timer as when you use the pen for the first time. You no longer need to store it in the fridge (though you can do so if you wish) and must use the pen within the above time frames

Is this medication genuine?

The medication is is governed under UK regulations by NICE & the MHRA. The medication is only sourced via UK based pharmacies who use official UK wholesalers to ensure you receive a genuine product from the manufacturer. Please see this notice from Novo Nordisk on how to spot a fake medication: Novo Nordisk Fake Ozempic Warning.

Do you have a Distance Selling Logo?

No. As of 1st January 2021, websites selling Prescription-Only Medicines can no longer and are no longer required to display the little green & white Distance Selling Logo, as this was an EU mandate, not a UK one. A UK version is in the pipeline.

Are you a pharmacy?

No. We are not a registered pharmacy. We act as a third party company offering a service to you. Most pharmacies do not offer a service other than prescribing, dispensing or selling medications - we offer a service centred around regular aftercare and check ins which not all online pharmacies are able to offer due to the nature of their business model. However, we use a registered prescriber and we source the medication from UK registered pharmacies that are licensed and regulated by the General Pharmaceutical Council. We only share your personal details with the prescriber and the pharmacy that will oversee your medication.

What is the difference between Off-Licence & Off-Label?

Liraglutide and Semaglutide is partly licensed for weight loss (Saxenda and Wegovy), whereas Dulaglutide and other forms of Semaglutide (Ozempic & Rybelsus) are licensed for diabetes. To get a medicine license, a medication goes through rigorous testing & clinical trials. It is then granted a license for a specific purpose by the Medicines and Healthcare Regulatory Authority (MHRA) for the UK. The license will include information on what the medicine is for, who the medicine is for and the parameters in which it can be used.

Prescribing Off-Licence means prescribing the medication outside of the licence's parameters.

Prescribing Off-Label means prescribing a drug for a different purpose than what it is licensed for.

For example, Rybelsus is currently licensed for diabetes but can be prescribed for weight loss if a person is deemed safe & suitable, it is clinically justifiable & reasonable, and you are made fully aware of the pros & cons alongside the fact that it is unlicensed for weight loss.

Please contact us if you would like more information regarding this or information on the current clinical trials of the medications for weight loss.

Have you tried non-medicated weight loss?

Free NHS 12 Week Plan

Learn more about medication for weight loss:

What is it?